Recombinant Human Syndecan-1/SDC1 Protein (Fc Tag)

Specifications

Catalog number

PKSH033514-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Syndecan-1 is a single-pass type I membrane protein that belongs to the syndecan proteoglycan family. The syndecans mediate cell binding; cell signaling; and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. Human SDC1 is synthesized as a 310 amino acid precursor that contains a 22 amino acid signal sequence; and a 288 amino acid mature chain. The Syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation; cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered Syndecan-1 expression has been detected in several different tumor types.

Abbreviation

Syndecan-1; SDC1

Synonyms

CD138; SDC; SDC1; SYND1; Syndecan-1

UniProt

P18827

Accession Number

AAH08765.1

Expression System

HEK293 Cells

Tag

C-Fc

Sequence

Gln18-Glu251

Field of Research

Signal Transduction; Neuroscience; Cancer; metabolism; Stem cells

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

51.0 kDa

Observed Molecular Weight

80-90 kDa

Citation 01

https://www.karger.com/Article/Abstract/517628

Species

Human