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Product details

Recombinant Human SLAMF6/Ly108 Protein (aa 28-225, His Tag)

Catalog number PKSH033521-01

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Price for PKSH033521-01

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Size / count 10 µg

Specifications

Catalog number
PKSH033521-01
Size / count
10 µg
Dry ice
No
Hazardous
No
Discontinued
No
Background
SLAM Family Member 6 (SLAMF6) is a 60 kD single-pass type I membrane protein that belongs to the SLAM subgroup of the CD2 family. Human SLAMF6/ NTB-A contains a 205 amino acid extracellular domain (ECD) with one Ig-like V-set and one Ig-like C2-set domain; a 21 amino acid transmembrane segment and an 84 amino acid cytoplasmic domain; with two immunoreceptor tyrosine-based switch motifs. SLAMF6 is a homodimer. SLAMF6 can interact with PTN6 and; upon phosphorylation; with PTN11 and SH2D1A/SAP. Phosphorylation-dependent NTB-A association with SAP is required for full production of IFN-γ by NK cells and independent of EAT-2 binding. It Triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors. On B cells; NTB-A modulates immunoglobulin class switching and the balance between tolerance and autoimmunity.
Abbreviation
SLAMF6; Ly108
Synonyms
Activating NK Receptor; CD352; KALI; Ly108; NK-T-B-Antigen; NTB-A; NTBA; SF2000; SLAM Family Member 6; SLAMF6
UniProt
Q96DU3
Accession Number
Q96DU3
Expression System
HEK293 Cells
Tag
C-His
Sequence
Leu28-Lys225
Field of Research
Immunology
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
23.4 kDa
Observed Molecular Weight
30-50 kDa
Species
Human

Frequently Asked Questions

What is the catalog number for Recombinant Human SLAMF6/Ly108 Protein (aa 28-225, His Tag)?

The catalog number for Recombinant Human SLAMF6/Ly108 Protein (aa 28-225, His Tag) is PKSH033521.

What sizes are available for Recombinant Human SLAMF6/Ly108 Protein (aa 28-225, His Tag)?

Recombinant Human SLAMF6/Ly108 Protein (aa 28-225, His Tag) is available in the following size(s): 10 µg, 50 µg.

How many pack sizes does Recombinant Human SLAMF6/Ly108 Protein (aa 28-225, His Tag) come in?

Recombinant Human SLAMF6/Ly108 Protein (aa 28-225, His Tag) is available in 2 different pack sizes.

Is Recombinant Human SLAMF6/Ly108 Protein (aa 28-225, His Tag) in stock?

Recombinant Human SLAMF6/Ly108 Protein (aa 28-225, His Tag) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Human SLAMF6/Ly108 Protein (aa 28-225, His Tag)?

Recombinant Human SLAMF6/Ly108 Protein (aa 28-225, His Tag) is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Human SLAMF6/Ly108 Protein (aa 28-225, His Tag)?

Estimated delivery time for Recombinant Human SLAMF6/Ly108 Protein (aa 28-225, His Tag) is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Human SLAMF6/Ly108 Protein (aa 28-225, His Tag)?

The safety data sheet for Recombinant Human SLAMF6/Ly108 Protein (aa 28-225, His Tag) is available here: https://789.bio/eb/OSi1aD.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

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