Recombinant Human Semaphorin 3A/SEMA3A Protein (His & Flag Tag)

Specifications

Catalog number

PKSH033535-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Emaphorin-3A is a secreted protein which belongs to the semaphorin family. Semaphorins are a family of secreted and cell-bound signaling molecules defined by the presence of a common 500 aa Sema domain.This protein can function as either a chemorepulsive agent; inhibiting axonal outgrowth; or as a chemoattractive agent; stimulating the growth of apical dendrites. In both cases; the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines.

Abbreviation

Semaphorin 3A; SEMA3A

Synonyms

Hsema-I; Hsema-III; SEMA1; SEMA3A; SEMAD; SemD; Sema III; Semad; Semaphorin III; coll-1

UniProt

Q14563

Accession Number

Q14563

Expression System

HEK293 Cells

Tag

N-His-Flag

Sequence

Lys26-Phe546

Field of Research

Cardiovascular; Neuroscience

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

61.3 kDa

Observed Molecular Weight

70-75 kDa

Species

Human