Recombinant Human S100A4 Protein (His Tag)

Specifications

Catalog number

PKSH033548-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

S100A4 is a member of the S100 family of proteins. The S100 family is further classified as a member of the EF-hand superfamily of Ca++-binding proteins. These participate in both calcium-dependent and calcium-independent protein-protein interactions. The hallmark of this superfamily is the EF-hand motif that consists of a Ca++-binding site flanked by two α-helices (helix E and helix F) that were originally identified in a right-handed model of carp muscle calcium-binding protein. Human S100A4 is 101 amino acids (aa) in length. It contains two EF hand domains, one between aa 12-47, and a second between aa 50-85. S100A4 activity has been associated with cell transformation. It seems likely this is either coincidental, or a consequence, rather than a cause of transformation.

Abbreviation

S100A4

Synonyms

18A2;42A; CAPL; Calvasculin; FSP1; MTS1; Metastasin; P9KA; PEL98; Placental calcium-binding protein; Protein Mts1; Protein S100-A4; S100 calcium-binding protein A4; S100A4

UniProt

P26447

Accession Number

P26447

Expression System

E.coli

Tag

C-His

Sequence

Met1-Lys101

Field of Research

Signal Transduction; Cardiovascular; Cancer

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

12.6 kDa

Observed Molecular Weight

13 kDa

Species

Human