Recombinant Human CD155/PVR/NECL5 Protein (mFc Tag)

Specifications

Catalog number

PKSH033561-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Poliovirus Receptor (PVR) is a 70 kDa type I transmembrane single-span glycoprotein that belongs to the nectin-like (Necl) family and was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV) ; an etiologic agent of the central nervous system disease poliomyelitis. PVR contains three Ig-like extracellular domains; a transmembrane segment; and a cytoplasmic tail. The normal cellular function of PVR maybe the involvement of intercellular adhension between epithelial cells. Alternate splicing of the PVR mRNA yields four different isoforms (α; β; γ; and δ) with identical extracellular domains.

Abbreviation

CD155; PVR; NECL5

Synonyms

CD155; NECL-5; Nectin-Like Protein 5; PVR; PVS; Poliovirus Receptor

UniProt

P15151

Accession Number

P15151

Expression System

HEK293 Cells

Tag

C-mFc

Sequence

Trp21-Asn343

Field of Research

Microbiology

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

61.7 kDa

Observed Molecular Weight

80-110 kDa

Species

Human