Recombinant Human CD31/PECAM1 Protein (Fc Tag)

Specifications

Catalog number

PKSH033567-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Semaphorin-4G is the least characterized of the seven known Class 4 transmembrane semaphorin glycoproteins. Class 4 semaphorins play multiple roles in cell attraction or repulsion, such as development of nerve pathways in the brain, promoting or inhibiting proliferation, in some cases organizing immune cell interactions. Semaphorin-4G can be expressed early in development in the central and peripheral nervous systems and in sensory ograns, such as cochlea, olfactory epithelium, vomeronasal organ and retina. In adults, Semaphorin-4G can be found in liver, kidney and brain. The human Semaphorin-4G precursor consists of a 17 amino acids signal sequence, a 658 amino acids extracellular domain, a 21 amino acids transmembrane domain, a 142 amino acids cytoplasmic domain with one Ser/Thr phosphorylation site.

Abbreviation

CD31; PECAM1

Synonyms

CD31; EndoCAM; GPIIA; PECA1; PECAM-1; PECAM1 ; Platelet endothelial cell adhesion molecule

UniProt

P16284

Accession Number

AAH22512.1

Expression System

HEK293 Cells

Tag

C-Fc

Sequence

Gln28-Lys601

Field of Research

Signal Transduction; Cardiovascular; Cancer; immunology; Stem cells

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

91.6 kDa

Observed Molecular Weight

110-130 kDa

Species

Human