Recombinant Human Osteoprotegerin/TNFRSF11B Protein (His Tag) — image 1 of 3

Product details

Recombinant Human Osteoprotegerin/TNFRSF11B Protein (His Tag)

Q: What is the catalog number for Recombinant Human Osteoprotegerin/TNFRSF11B Protein (His Tag)?

The catalog number for Recombinant Human Osteoprotegerin/TNFRSF11B Protein (His Tag) is PKSH033573.

Q: What is the estimated delivery time for Recombinant Human Osteoprotegerin/TNFRSF11B Protein (His Tag)?

Estimated delivery time for Recombinant Human Osteoprotegerin/TNFRSF11B Protein (His Tag) is approximately 15 business day(s), depending on your location.

Q: Where can I find the safety data sheet (SDS/MSDS) for Recombinant Human Osteoprotegerin/TNFRSF11B Protein (His Tag)?

The safety data sheet for Recombinant Human Osteoprotegerin/TNFRSF11B Protein (His Tag) is available here: https://789.bio/eb/qHyff5.

Q: What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Q: Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

Q: What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

Catalog number PKSH033573-01

Choose a variant (2 options)

Selecting a variant updates its price, size and availability.

Price for PKSH033573-01

Size / count 10 µg

Specifications

Catalog number: PKSH033573-01
Size / count: 10 µg
Dry ice: No
Hazardous: No
Discontinued: No
Background: TNFRSF11B is a secreted protein; containing 2 death domains and 4 TNFR-Cys repeats. TNFRSF11B is a decoy receptor for the receptor activator of nuclear factor kappa B ligand (RANKL) . By binding RANKL; TNFRSF11B inhibits nuclear kappa B (NF-κB) which is a central and rapid acting transcription factor for immune-related genes; and a key regulator of inflammation; innate immunity; and cell survival and differentiation. TNFRSF11B levels are influenced by voltage-dependent calcium channelsCav1.2. TNFRSF11B can reduce the production of osteoclasts by inhibiting the differentiation of osteoclast precursors (osteoclasts are related to monocytes/macrophages and are derived from granulocyte/macrophage-forming colony units (CFU-GM) ) into osteoclasts and also regulates the resorption of osteoclasts in vitroand in vivo. TNFRSF11B binding to RANKL on osteoblast/stromal cells; blocks the RANKL-RANK ligand interaction between osteoblast/stromal cells and osteoclast precursors. This has the effect of inhibiting the differentiation of the osteoclast precursor into a mature osteoclast.
Abbreviation: Osteoprotegerin; TNFRSF11B
Synonyms: OCIF; OPG; Osteoclastogenesis inhibitory factor; Osteoprotegerin; PDB5; TNFRSF11B; TR1 ; Tumor necrosis factor receptor superfamily member 11B
UniProt: O00300
Accession Number: O00300
Expression System: HEK293 Cells
Tag: C-His
Sequence: Glu22-Leu401
Field of Research: Signal Transduction; Cardiovascular; immunology; metabolism
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Purity: > 95 % as determined by reducing SDS-PAGE.
Bioactivity: Not validated for activity
Reconstitution: Please refer to the printed manual for detailed information.
Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight: 44.7 kDa
Observed Molecular Weight: 57 kDa
Species: Human

Frequently Asked Questions

What is the catalog number for Recombinant Human Osteoprotegerin/TNFRSF11B Protein (His Tag)?

The catalog number for Recombinant Human Osteoprotegerin/TNFRSF11B Protein (His Tag) is PKSH033573.

What sizes are available for Recombinant Human Osteoprotegerin/TNFRSF11B Protein (His Tag)?

Recombinant Human Osteoprotegerin/TNFRSF11B Protein (His Tag) is available in the following size(s): 10 µg, 50 µg.

How many pack sizes does Recombinant Human Osteoprotegerin/TNFRSF11B Protein (His Tag) come in?

Recombinant Human Osteoprotegerin/TNFRSF11B Protein (His Tag) is available in 2 different pack sizes.

Is Recombinant Human Osteoprotegerin/TNFRSF11B Protein (His Tag) in stock?

Recombinant Human Osteoprotegerin/TNFRSF11B Protein (His Tag) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Human Osteoprotegerin/TNFRSF11B Protein (His Tag)?

Recombinant Human Osteoprotegerin/TNFRSF11B Protein (His Tag) is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Human Osteoprotegerin/TNFRSF11B Protein (His Tag)?

Estimated delivery time for Recombinant Human Osteoprotegerin/TNFRSF11B Protein (His Tag) is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Human Osteoprotegerin/TNFRSF11B Protein (His Tag)?

The safety data sheet for Recombinant Human Osteoprotegerin/TNFRSF11B Protein (His Tag) is available here: https://789.bio/eb/qHyff5.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.