Recombinant Human Nucleobindin-2/NUCB2 Protein

Specifications

Catalog number

PKSH033575-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Nesfatin-1 is a metabolic polypeptide encoded in the N-terminal region of the precursor protein, Nucleobindin2 (NUCB2) . Nesfatin-1 is a neuropeptide produced in the hypothalamus of mammals. It participates in the regulation of hunger and fat storage. Nesfatin-1 is also expressed in other areas of the brain, and in pancreatic islets β-cells, gastric endocrine cells and adipocytes. Nesfatin-1 suppresses food intake and can regulate energy metabolism in a Leptin independent manner. Nesfatin-1 may also exert hypertensive roles and modulate blood pressure through directly acting on peripheral arterial resistance.

Abbreviation

Nucleobindin-2; NUCB2

Synonyms

DNA-binding protein NEFA; Gastric cancer antigen Zg4; NEFA; NUCB2; Nesfatin-1; Nucleobindin-2; Prepronesfatin

UniProt

P80303

Accession Number

P80303

Expression System

E.coli

Tag

None

Sequence

Val25-Leu106

Field of Research

Signal Transduction; epigenetics and nuclear signal

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

9.6 kDa

Observed Molecular Weight

10 kDa

Species

Human