Recombinant Human Natriuretic Peptides B/NPPB Protein (His Tag)

Specifications

Catalog number

PKSH033585-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Human Natriuretic peptides B acts as a cardiac hormone; it is associated with many biological actions; such as diuresis; natriuresis; vasorelaxation; which inhibits the secretion of rennin and aldosterone. It acts as a paracrine antifibrotic factor in the heart. Natriuretic peptides B can help restore the body balance of salt and water; improves the heart function. Natriuretic peptides B binds and stimulates the cGMP production of the NPR1 receptor and binds the clearance receptor NPR3.

Abbreviation

NPPB

Synonyms

Gamma-Brain Natriuretic Peptide; NPPB; Natriuretic Peptides B

UniProt

P16860

Accession Number

P16860

Expression System

E.coli

Tag

N-His

Sequence

His27-His134

Field of Research

Signal Transduction; Cardiovascular; Neuroscience

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

14.2 kDa

Observed Molecular Weight

16 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 1mM EDTA, 1mM DTT, 20% Glycerol, pH 7.4.

Species

Human