Recombinant Human ACP1/LMW-PTP Protein (His Tag)

Specifications

Catalog number

PKSH033598-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Low Molecular Weight Phosphotyrosine Protein Phosphatase (LMW-PTP) is a member of the low molecular weight phosphotyrosine protein phosphatase family. LMW-PTP serves as an acid phosphatase and a protein tyrosine phosphatase (PTPase) by hydrolyzing protein tyrosine phosphate to protein tyrosine and orthophosphate. LMW-PTP can be detected in all human tissues, including adipocytes. LMW-PTP is a cytosolic enzyme that regulate cell proliferation and growth of leiomyomas during dephosphorylation of the PDGF receptor. In addition, LMW-PTP plays an important role in the regulation of physiological functions, such as stress resistance and synthesis of the polysaccharide capsule.

Abbreviation

ACP1; LMW-PTP

Synonyms

ACP1; Adipocyte Acid Phosphatase; HAAP; LMW-PTP; LMW-PTPase; Low Molecular Weight Cytosolic Acid Phosphatase; Low Molecular Weight Phosphotyrosine Protein Phosphatase; Red Cell Acid Phosphatase 1

UniProt

P24666

Accession Number

P24666-2

Expression System

E.coli

Tag

C-His

Sequence

Ala2-His158

Field of Research

Cell Biology, Cancer

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

19.0 kDa

Observed Molecular Weight

18 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 10% Glycerol, pH 8.0.

Species

Human