Recombinant Human IL17B/IL-17B Protein (Fc Tag)

Specifications

Catalog number

PKSH033628-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Interleukin-17B (IL-17B) is a member of IL-17 cytokines family that plays important roles in host defence responses and inflammatory diseases. In addition to IL-17B, members of the IL-17 family include IL-17A, IL-17C, IL-17D, IL-17E and IL-17F. The six IL-17 cytokines are highly conserved at C terminus, and contain five spatially conserved cysteine residues that mediate dimerization. Expression of IL-17B protein has been reported in neurons, testis, ovary, stomach, pancreas, small intestine and chondrocytes. IL-17B binds to Interleukine-17 receptor B (IL-17 RB) and induces the production of inflammatory cytokines and the infiltration of inflammatory immune cells.

Abbreviation

IL17B; IL-17B

Synonyms

UNQ; PRO; Cytokine ZCYTO; ZCYTO; Cytokine ZCYTO7; IL-17B; IL-20; IL20; NIRF; ZCYTO7; IL17B; UNQ516; PRO1031

UniProt

Q9UHF5

Accession Number

Q9UHF5

Expression System

HEK293 Cells

Tag

C-Fc

Sequence

Gln21-Phe180

Field of Research

Immunology

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

45.1 kDa

Observed Molecular Weight

48 kDa

Species

Human