Recombinant Human CGA&CGB3 Heterodimer Protein (His & Flag Tag)

Specifications

Catalog number

PKSH033665-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Glycoprotein hormones alpha chain, also known as CGA, belongs to the glycoprotein hormones subunit alpha family. The subunit of CGA is a heterodimer consists of a common alpha chain and a unique beta chain which confers biological specificity to thyrotropin, lutropin, follitropin and gonadotropin. It has positive regulation of cell migration, cell proliferation and transcription from RNA polymerase II promoter and participates in the peptide hormone processing and signal transduction.

Abbreviation

CGA&CGB3 Heterodimer

Synonyms

Beta-NGF; Beta-Nerve Growth Factor; NGF; NGFB

UniProt

P01215; P0DN86

Accession Number

P01215&P0DN86

Expression System

HEK293 Cells

Tag

C-Flag & C-His

Sequence

Ala25-Ser116&Ser21-Gln165

Field of Research

Signal Transduction; Neuroscience; Cancer; Developmental Biology; metabolism

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

11.6&16.6 kDa

Observed Molecular Weight

22&30-35 kDa

Species

Human