Recombinant Human GALK1/Galactokinase Protein (His Tag)

Specifications

Catalog number

PKSH033673-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Galactokinase belongs to the GHMP kinase family and GalK subfamily. Galactokinase is more important to the galactose metabolism pathway. It modifies galactose to create a similar molecule called Galactose-1-Phosphate.Thus; a series of additional steps converts Galactose-1-Phosphate to another simple sugar Glucose; which is the main energy source for most cells. Galactokinase deficiency results in Galactosemia II; an autosomal recessive deficiency characterized by congenital cataracts during infancy and presenile cataracts in the adult population. The cataracts are secondary to accumulation of Galactitol in the lenses.

Abbreviation

GALK1; Galactokinase

Synonyms

GALK; GALK1; Galactokinase; Galactose Kinase

UniProt

P51570

Accession Number

P51570

Expression System

E.coli

Tag

C-His

Sequence

Met1-Leu392

Field of Research

Signal Transduction; Cell biology; Cancer; epigenetics and nuclear signal; metabolism

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 85 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

43.3 kDa

Observed Molecular Weight

45 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.

Species

Human