Recombinant Human FABP6/I-BABP Protein (His Tag)

Specifications

Catalog number

PKSH033681-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Fatty Acid-Binding Protein 6 (FABP6) is cytoplasmic protein that binds long-chain fatty acids and other hydrophobic ligands which belongs to the calycin superfamily. FABP6 expression is restricted in the small intestine to the ileum where it is involved in the enterohepatic circulation of bile acids. FABP6 forms a beta-barrel structure that accommodates the hydrophobic ligand in its interior. Isoform 2 is expressed in colorectal adenocarcinomas and their adjacent normal mucosa (at protein level) . Isoform 1 is expressed in the jejunum, ileum, cecum and ascending colon intestine. FABP6 plays a role in fatty acid uptake, transport, and metabolism. FABP6 stimulates gastric acid and pepsinogen secretion. It seems to be able to bind to bile salts and bilirubins.

Abbreviation

FABP6; I-BABP

Synonyms

FABP6; Fatty Acid-Binding Protein 6; GT; Gastrotropin; I-15P; I-BABP; ILBP; ILLBP; Ileal Lipid-Binding Protein; Intestinal 15 kDa Protein; Intestinal Bile Acid-Binding Protein

UniProt

P51161

Accession Number

AAH22489.1

Expression System

E.coli

Tag

N-His

Sequence

Met1-Ala128

Field of Research

Signal Transduction; Cardiovascular; Cancer; metabolism

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

16.6 kDa

Observed Molecular Weight

15 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 0.5mM DTT, 50% Glycerol, pH 8.0.

Species

Human