Recombinant Human FABP4/A-FABP Protein (His Tag)

Specifications

Catalog number

PKSH033682-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Fatty Acid-Binding Protein 4 (FABP4) is a cytoplasm protein that belongs to the fatty-acid binding protein (FABP) family of calycin superfamily. Fatty acid binding proteins are a family of small; highly conserved; cytoplasmic proteins that bind long-chain fatty acids. FABP4 is expressed in a differentiation-dependent fashion in adipocytes and is a critical gene in the regulation of the biological function of these cells. FABP4 is thought to participate in Lipid transport protein in adipocytes. FABP4 binds to the long chain fatty acids and retinoic acid; delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus. FABP4 modulates inflammatory responses and cholesterol ester accumulation. FABP4 is a plasma marker of metabolic disturbances in HIV-infected patients; and therefore; could serve to guide therapeutic intervention in this group of patients.

Abbreviation

FABP4; A-FABP

Synonyms

A-FABP; AFABP; ALBP; Adipocyte Lipid-Binding Protein; Adipocyte-Type Fatty Acid-Binding Protein; Fatty Acid-Binding Protein 4; Fatty Acid-Binding Protein Adipocyte; HEL-S-104; aP2

UniProt

P15090

Accession Number

P15090

Expression System

E.coli

Tag

N-His

Sequence

Cys2-Ala132

Field of Research

Signal Transduction; Cardiovascular; Cancer; metabolism; Stem cells

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

16.9 kDa

Observed Molecular Weight

15 kDa

Species

Human