Recombinant Human CCL17/TARC Protein (His Tag)

Specifications

Catalog number

PKSH033735-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

C-C motif chemokine 17 (CCL17) is a novel CC chemokine, it belongs to the intercrine beta (chemokine CC) family. CCL17 is expressed at high levels in thymus, and at a lower level in lung, colon, and small intestine. CCL17 is also transiently expressed in stimulated peripheral blood mononuclear cells. Among CC chemokine family members, CCL17 has approximately 24 - 29% amino acid sequence identity with RANTES, MIP-1 alpha, MIP-1 beta, MCP-1, MCP-2 and MCP-3. CCL17 has been identified to be Chemotactic factor for T-lymphocytes but not monocytes or granulocytes. CCL17 plays a role in T-cell development in thymus and in trafficking and activation of mature T-cells.

Abbreviation

CCL17; TARC

Synonyms

ABCD-2; C-C motif chemokine 17; CC chemokine TARC; CCL17; MGC138273; SCYA17MGC138271; Small-inducible cytokine A17; T cell-directed CC chemokine; TARC; TARCA-152E5.3; Thymus an; chemokine (C-C motif) ligand 17; member 17; small inducible cytokine subfamily A (Cys-Cys)

UniProt

Q92583

Accession Number

Q92583

Expression System

HEK293 Cells

Tag

C-His

Sequence

Ala24-Ser94

Field of Research

Immunology

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

9.1 kDa

Observed Molecular Weight

13 kDa

Species

Human