Recombinant Human CEACAM1/CD66a Protein (His Tag)

Specifications

Catalog number

PKSH033739-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1) is a member of the Carcinoembryonic Antigen (CEA) family, which belongs to the immunoglobulin superfamily. CEACAM1 is originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it is found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. CEACAM1 mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. In addition, CEACAM1 plays a important role in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses.

Abbreviation

CEACAM1; CD66a

Synonyms

BGP; BGP-1; BGP1; Biliary Glycoprotein 1; CD66a; CEACAM1; Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1

UniProt

P13688

Accession Number

P13688

Expression System

HEK293 Cells

Tag

C-His

Sequence

Gln35-Gly428

Field of Research

Tags & Cell Markers; Microbiology; Cancer; immunology

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

44.3 kDa

Observed Molecular Weight

60-90 kDa

Species

Human