Recombinant Human AMIGO2 Protein (Fc Tag)

Specifications

Catalog number

PKSH033770-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Amphoterin-Induced Protein 2 (AMIGO2) is a single-pass type I membrane protein which belongs to the AMIGO family of immunoglobulin superfamily. Mature AMIGO2 contains an Ig-like C2-type (immunoglobulin-like) domain; 6 LRR (leucine-rich) repeats; a LRRCT domain; as well as a LRRNT domain. AMIGO2 is mainly expressed in in breast; ovary; cervix; and uterus; although lower in lung; colon; and rectum. AMIGO2 required for depolarization-dependent survival of cultured cerebellar granule neurons. AMIGO2 may mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. AMIGO2 may contribute to signal transduction through its intracellular domain; and may be required for tumorigenesis of a subset of gastric adenocarcinomas.

Abbreviation

AMIGO2

Synonyms

ALI1; AMIGO-2; Alivin-1; Amphoterin-Induced Protein 2; DEGA; Differentially Expressed in Gastric Adenocarcinomas

UniProt

Q86SJ2

Accession Number

Q86SJ2

Expression System

HEK293 Cells

Tag

C-Fc

Sequence

Gly39-His393

Field of Research

Neuroscience

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

67.5 kDa

Observed Molecular Weight

93 kDa

Species

Human