Recombinant Human ALDH1A3 Protein (His Tag)

Specifications

Catalog number

PKSH033774-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Aldehyde dehydrogenase 1 family member A3 (ALDH1A3), also known as retinaldehyde dehydrogenase 3 (RALDH3), is a member of the aldehyde dehydrogenase family known to metabolize a wide variety of aldehydes. ALDH1A3 specifically oxidizes retinal to retinoic acid (RA) and is differentially expressed in developing embryonic tissues and adult organs. The RA produced by ALDH1A3 in rodents contributes to the development of skin and hair follicles, brain, tooth buds, lungs, olfactory bulbs, kidneys, eyes, skeletal muscle and seminal vesicles. In recent research, ALDH1A3 could be as a marker of cancer stem cell to predict metastasis or clinical prognosis in many cancers.

Abbreviation

ALDH1A3

Synonyms

ALDH1A3; ALDH1A6; ALDH6; Aldehyde dehydrogenase 6; Aldehyde dehydrogenase family 1 member A3; MCOP8; RALDH-3; RALDH3; Retinaldehyde dehydrogenase 3

UniProt

P47895

Accession Number

P47895

Expression System

E.coli

Tag

N-His

Sequence

Met1-Pro512

Field of Research

Signal Transduction; Neuroscience; metabolism

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

57.5 kDa

Observed Molecular Weight

55-60 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 20% Glycerol, pH 7.5.

Species

Human