Recombinant Human 4-1BB/TNFRSF9 Protein (mFc Tag)

Specifications

Catalog number

PKSH033786-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Tumor necrosis factor receptor superfamily member 9 (TNFRSF9) is an inducible T cell surface protein belonging to the TNF receptor superfamily. It is a single-pass type I membrane protein which contains 4 TNFR-Cys repeats. The human and mouse proteins share 60% amino acid sequence identity. It is absent from naive T cells; but upregulated and continually expressed following T cell activation. It is a receptor for TNFSF9/4-1BBL; and possibly active during T cell activation.

Abbreviation

4-1BB; TNFRSF9

Synonyms

4-1BB ligand receptor; CD137; CDw137; ILA; T-cell antigen 4-1BB homolog; T-cell antigen ILA; TNFRSF9

UniProt

Q07011

Accession Number

Q07011

Expression System

HEK293 Cells

Tag

C-mFc

Sequence

Leu24-Gln186

Field of Research

Cell biology; Cancer; immunology; Stem cells

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 90 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

43.9 kDa

Observed Molecular Weight

50-70 kDa

Species

Human