Recombinant Human Integrin Beta-1/ITGB1 (C-6His)

Specifications

Catalog number

PKSH033841-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Integrin β-1 (ITGB1) belongs to the integrin β chain family. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. ITGB1 is an integrin unit associated with very late antigen receptors, which contains one VWFA domain. It is known to conjoin with α-3 subunit to create α3β1 complex that reacts to such molecules as netrin-1 and reelin.

Abbreviation

Integrin Beta-1; ITGB1

Synonyms

CD29; FNRB; Fibronectin Receptor Subunit Beta; ITGB1; Integrin Beta-1; MDF2; MSK12; VLA-4 Subunit Beta

UniProt

P05556

Accession Number

P05556

Expression System

HEK293 Cells

Tag

C-His

Sequence

Gln21-Asp728

Field of Research

Signal Transduction; Microbiology; Neuroscience; Cancer; Developmental Biology; metabolism; Stem cells

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 90 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

79.4 kDa

Observed Molecular Weight

100-130 kDa

Species

Human