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Product details

Recombinant Human CD3 epsilon/CD3E (C-mFC)

Catalog number PKSH033869-01

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Price for PKSH033869-01

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Size / count 10 µg

Specifications

Catalog number
PKSH033869-01
Size / count
10 µg
Dry ice
No
Hazardous
No
Discontinued
No
Background
T-Cell Surface Glycoprotein CD3 ε Chain (CD3ε) is a single-pass type I membrane protein. CD3ε contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3ε is a polypeptide encoded by the CD3E gene on chromosome 11 in humans. The T cell receptor-CD3 complex (TCR/CD3 complex) is involved in T-cell development and several intracellular signal-transduction pathways. This complex is critical for T-cell development and function, and represents one of the most complex transmembrane receptors. The T cell receptor-CD3 complex is unique in having ten cytoplasmic immunoreceptor tyrosine-based activation motifs (ITAMs) . TCR/CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.
Abbreviation
CD3 epsilon; CD3E
Synonyms
CD3E; CD3e; T-Cell Surface Antigen T3/Leu-4 Epsilon Chain; T-Cell Surface Glycoprotein CD3 Epsilon Chain; T3E
UniProt
P07766
Accession Number
P07766
Expression System
HEK293 Cells
Tag
C-mFC
Sequence
Gln22-Thr48
Applications
ELISA
Field of Research
Immunology; Stem cells
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Immobilized Anti-Human/Monkey CD3E mAb at 2μg/ml (100 μl/well) can bind Human CD3E-mFc.The ED50 of Human CD3E-mFc is 28.99 ng/ml.
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
28.5 kDa
Observed Molecular Weight
32-40 kDa
Species
Human

Frequently Asked Questions

What is the catalog number for Recombinant Human CD3 epsilon/CD3E (C-mFC)?

The catalog number for Recombinant Human CD3 epsilon/CD3E (C-mFC) is PKSH033869.

What sizes are available for Recombinant Human CD3 epsilon/CD3E (C-mFC)?

Recombinant Human CD3 epsilon/CD3E (C-mFC) is available in the following size(s): 10 µg, 50 µg.

How many pack sizes does Recombinant Human CD3 epsilon/CD3E (C-mFC) come in?

Recombinant Human CD3 epsilon/CD3E (C-mFC) is available in 2 different pack sizes.

Is Recombinant Human CD3 epsilon/CD3E (C-mFC) in stock?

Recombinant Human CD3 epsilon/CD3E (C-mFC) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Human CD3 epsilon/CD3E (C-mFC)?

Recombinant Human CD3 epsilon/CD3E (C-mFC) is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Human CD3 epsilon/CD3E (C-mFC)?

Estimated delivery time for Recombinant Human CD3 epsilon/CD3E (C-mFC) is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Human CD3 epsilon/CD3E (C-mFC)?

The safety data sheet for Recombinant Human CD3 epsilon/CD3E (C-mFC) is available here: https://789.bio/eb/iPWXn9.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

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