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Product details

Recombinant Human ILDR2 (C-Fc)

Catalog number PKSH033884-01

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Price for PKSH033884-01

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Size / count 10 µg

Specifications

Catalog number
PKSH033884-01
Size / count
10 µg
Dry ice
No
Hazardous
No
Discontinued
No
Background
ILDR2 is a member of the B7-like family of proteins that regulate T cell activity, is also a known endoplasmic reticulum molecule that regulates lipid homeostasis. The human ILDR2 lumenal domain shares a 99% and 98% homology with the mouse and rat respectively. The human gene encoding ILDR2 is located in a region on Chr1q23–25 that has been associated with type 2 diabetes. ILDR2 plays critical roles in hepatic clearance of lipoproteins and in lipid homeostasis. ILDR2 regulates human dendritic cells (DC2 cells, a subpopulation of polarized DCs that promotes Th2 differentiation) . Recent publications reported that ILDR2 displayed negative regulatory functions on human and mouse T cells in various experimental systems. Fusion protein of ILDR2 lumenal domain with an Fc fragment, displays therapeutic effects in collagen-induced arthritis (CIA), a mouse model of rheumatoid arthritis (RA) . ILDR2 represents a novel B7-like ligand that exerts negative immune modulation via interaction with a putative counterpart receptor expressed on activated T cells.
Abbreviation
ILDR2
Synonyms
Immunoglobulin-like domain containing receptor; Ildr; Dbsm; C1orf; DJ782G; Angulin; Angulin-3; Dbsm1; DJ782G3.1; immunoglobulin-like domain containing receptor 2; LISCH-Like; C1orf32; ILDR2
UniProt
Q71H61
Accession Number
Q71H61
Expression System
HEK293 Cells
Tag
C-Fc
Sequence
Leu21-Glu186
Field of Research
Immunology
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
45.8 kDa
Observed Molecular Weight
47-52 kDa
Species
Human

Frequently Asked Questions

What is the catalog number for Recombinant Human ILDR2 (C-Fc)?

The catalog number for Recombinant Human ILDR2 (C-Fc) is PKSH033884.

What sizes are available for Recombinant Human ILDR2 (C-Fc)?

Recombinant Human ILDR2 (C-Fc) is available in the following size(s): 10 µg, 50 µg.

How many pack sizes does Recombinant Human ILDR2 (C-Fc) come in?

Recombinant Human ILDR2 (C-Fc) is available in 2 different pack sizes.

Is Recombinant Human ILDR2 (C-Fc) in stock?

Recombinant Human ILDR2 (C-Fc) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Human ILDR2 (C-Fc)?

Recombinant Human ILDR2 (C-Fc) is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Human ILDR2 (C-Fc)?

Estimated delivery time for Recombinant Human ILDR2 (C-Fc) is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Human ILDR2 (C-Fc)?

The safety data sheet for Recombinant Human ILDR2 (C-Fc) is available here: https://789.bio/eb/H8mLq1.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

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