Recombinant Human CD79B/B29 (C-Fc)

Specifications

Catalog number

PKSH033891-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

CD79B is a single-pass type I membrane protein. CD79B contains one Ig-like V-type domain and one ITAM domain. CD79B is required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR), which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. CD79B enhances phosphorylation of CD79A, possibly by recruiting kinases that phosphorylate CD79A or by recruiting proteins that bind to CD79A and protect it from dephosphorylation.

Abbreviation

CD79B; B29

Synonyms

B-Cell Antigen Receptor Complex-Associated Protein Beta Chain; B-Cell-Specific Glycoprotein B29; B29; CD79B; CD79b; IGB; Ig-Beta; Immunoglobulin-Associated B29 Protein

UniProt

P40259

Accession Number

P40259

Expression System

HEK293 Cells

Tag

C-Fc

Sequence

Ala29-Asp159

Field of Research

Immunology

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

42.1 kDa

Observed Molecular Weight

45-65 kDa

Species

Human