Recombinant Human TMED1 (C-Fc) — image 1 of 3

Product details

Recombinant Human TMED1 (C-Fc)

Q: What is the catalog number for Recombinant Human TMED1 (C-Fc)?

The catalog number for Recombinant Human TMED1 (C-Fc) is PKSH033904.

Q: What sizes are available for Recombinant Human TMED1 (C-Fc)?

Recombinant Human TMED1 (C-Fc) is available in the following size(s): 10 µg, 50 µg.

Q: How many pack sizes does Recombinant Human TMED1 (C-Fc) come in?

Recombinant Human TMED1 (C-Fc) is available in 2 different pack sizes.

Q: Is Recombinant Human TMED1 (C-Fc) in stock?

Recombinant Human TMED1 (C-Fc) is currently made to order / not held in immediate stock. Contact us for lead time.

Q: Who manufactures Recombinant Human TMED1 (C-Fc)?

Recombinant Human TMED1 (C-Fc) is manufactured by Elabscience.

Q: What is the estimated delivery time for Recombinant Human TMED1 (C-Fc)?

Estimated delivery time for Recombinant Human TMED1 (C-Fc) is approximately 15 business day(s), depending on your location.

Q: Where can I find the safety data sheet (SDS/MSDS) for Recombinant Human TMED1 (C-Fc)?

The safety data sheet for Recombinant Human TMED1 (C-Fc) is available here: https://789.bio/eb/fzrvf1.

Q: What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Q: Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Q: Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Catalog number PKSH033904-01

Choose a variant (2 options)

Selecting a variant updates its price, size and availability.

Price for PKSH033904-01

Size / count 10 µg

Specifications

Catalog number: PKSH033904-01
Size / count: 10 µg
Dry ice: No
Hazardous: No
Discontinued: No
Background: TMED1 (Transmembrane Emp24 domain-containing protein 1) is a member of the TMED family of proteins (gene name TMED1) . The TMED family of proteins are localized to membranes of the early secretory pathway, including the endoplasmic reticulum and Golgi, and function in vesicular protein trafficking. TMED1 is a 59 kDa monomer and has been reported to exist as homodimer. It contains 1 GOLD domain and is widely expressed. TMED1 is important in regulating innate immune signaling through its interaction with ST2L. Specifically, the GOLD domain in TMED1 interacts with the TIR domain of ST2L, a receptor for IL 33. This interaction promotes ST2L association with IL-33, allowing downstream signaling cascade activating MAP kinases, p38, and JNK. Studies have shown knockdown of TMED-1 in HUVECs impairs the IL-33 induced response resulting in reduction of IL-6 and IL-8 productions.
Abbreviation: TMED1
Synonyms: IL-1RL1LG; IL1RL1-Binding Protein; IL1RL1LG; IL1RL1LGIL1RL1-binding protein; Il1rl1l; ST2L; T1/ST2 receptor binding protein; TMED1; Tp24
UniProt: Q13445
Accession Number: Q13445
Expression System: HEK293 Cells
Tag: C-Fc
Sequence: Ala24-Asn194
Field of Research: Cell biology
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Purity: > 90 % as determined by reducing SDS-PAGE.
Bioactivity: Not validated for activity
Reconstitution: Please refer to the printed manual for detailed information.
Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight: 46.3 kDa
Observed Molecular Weight: 55-65 kDa
Species: Human

Frequently Asked Questions

What is the catalog number for Recombinant Human TMED1 (C-Fc)?

The catalog number for Recombinant Human TMED1 (C-Fc) is PKSH033904.

What sizes are available for Recombinant Human TMED1 (C-Fc)?

Recombinant Human TMED1 (C-Fc) is available in the following size(s): 10 µg, 50 µg.

How many pack sizes does Recombinant Human TMED1 (C-Fc) come in?

Recombinant Human TMED1 (C-Fc) is available in 2 different pack sizes.

Is Recombinant Human TMED1 (C-Fc) in stock?

Recombinant Human TMED1 (C-Fc) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Human TMED1 (C-Fc)?

Recombinant Human TMED1 (C-Fc) is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Human TMED1 (C-Fc)?

Estimated delivery time for Recombinant Human TMED1 (C-Fc) is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Human TMED1 (C-Fc)?

The safety data sheet for Recombinant Human TMED1 (C-Fc) is available here: https://789.bio/eb/fzrvf1.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.