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Product details

Recombinant Human SIRPB2 (C-Fc)

Catalog number PKSH033926-01

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Price for PKSH033926-01

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Size / count 10 µg

Specifications

Catalog number
PKSH033926-01
Size / count
10 µg
Dry ice
No
Hazardous
No
Discontinued
No
Background
Signal-regulatory protein beta-2 (SIRP-beta-2), is a monomeric single pass type I membrane glycoprotein, belongs to the SIRP/SHPS (CD172) family of the immunoglobulin (Ig) superfamily. The SIRP family are paired receptors that have similar extracellular domains but differing C-terminal domains and functions. A positively charged residue within the transmembrane domain, in analogy to SIRP-beta-1, is implicated to mediate interaction with the adaptor DAP12 protein, which contains immunoreceptor tyrosine-based activation motifs (ITAMs) . Proteins in the SIRP family are typically expressed in immune cells, especially in the myeloid lineages . Based on expression patterns, SIRPs are thought to have roles in immune regulation. SIRP family members role in innate immunity and host defense has potential significance as a therapeutic target in cancer and inflammation. There are currently no known mouse or rat homologs for this protein.
Abbreviation
SIRPB2
Synonyms
PTPN1L; PTPNS1L3; SIRP beta 2; SIRP-beta-2; SIRPG; Signal-Regulatory Protein Beta 2; Signal-Regulatory Protein Beta-2; dJ776F14.2
UniProt
Q5JXA9
Accession Number
Q5JXA9
Expression System
HEK293 Cells
Tag
C-Fc
Sequence
Gln33-Gly287
Field of Research
Signal Transduction
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
55.2 kDa
Observed Molecular Weight
80-95 kDa
Species
Human

Frequently Asked Questions

What is the catalog number for Recombinant Human SIRPB2 (C-Fc)?

The catalog number for Recombinant Human SIRPB2 (C-Fc) is PKSH033926.

What sizes are available for Recombinant Human SIRPB2 (C-Fc)?

Recombinant Human SIRPB2 (C-Fc) is available in the following size(s): 10 µg, 50 µg.

How many pack sizes does Recombinant Human SIRPB2 (C-Fc) come in?

Recombinant Human SIRPB2 (C-Fc) is available in 2 different pack sizes.

Is Recombinant Human SIRPB2 (C-Fc) in stock?

Recombinant Human SIRPB2 (C-Fc) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Human SIRPB2 (C-Fc)?

Recombinant Human SIRPB2 (C-Fc) is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Human SIRPB2 (C-Fc)?

Estimated delivery time for Recombinant Human SIRPB2 (C-Fc) is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Human SIRPB2 (C-Fc)?

The safety data sheet for Recombinant Human SIRPB2 (C-Fc) is available here: https://789.bio/eb/TuTOy5.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

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