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Product details

Recombinant Human GAS6 (C-6His)

Catalog number PKSH033928-01

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Price for PKSH033928-01

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Size / count 10 µg

Specifications

Catalog number
PKSH033928-01
Size / count
10 µg
Dry ice
No
Hazardous
No
Discontinued
No
Background
GAS6 (Growth arrest-specific protein 6) is also known as AXL receptor tyrosine kinase ligand, AXLLG, is a multimodular protein that is up-regulated by a wide variety of cell types in response to growth arrest. Gas6 binds and induces signaling through the receptor tyrosine kinases Axl, Dtk, and Mer whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses.
Abbreviation
GAS6
Synonyms
AXLLG; AXLLGAXL stimulatory factor; AXSFAXL receptor tyrosine kinase ligand; GAS-6; Gas6; growth arrest-specific 6; growth arrest-specific protein 6
UniProt
Q14393
Accession Number
Q14393-2
Expression System
HEK293 Cells
Tag
C-His
Sequence
Ala31-Ala678
Applications
ELISA
Field of Research
Signal Transduction; Cardiovascular; Stem cells
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Immobilized Human AXL-His at 10μg/ml (100 μl/well) can bind Human GAS6-His : Biotinylated by NHS-biotin prior to testing. The ED50 of Recombinant Human GAS6-His is 0.04466 ug/ml.
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
72.7 kDa
Observed Molecular Weight
80-90 kDa
Formulation
Supplied as a 0.2 μm filtered solution of PBS, 10% Glycerol, pH 7.4.
Species
Human

Frequently Asked Questions

What is the catalog number for Recombinant Human GAS6 (C-6His)?

The catalog number for Recombinant Human GAS6 (C-6His) is PKSH033928.

What sizes are available for Recombinant Human GAS6 (C-6His)?

Recombinant Human GAS6 (C-6His) is available in the following size(s): 10 µg, 50 µg.

How many pack sizes does Recombinant Human GAS6 (C-6His) come in?

Recombinant Human GAS6 (C-6His) is available in 2 different pack sizes.

Is Recombinant Human GAS6 (C-6His) in stock?

Recombinant Human GAS6 (C-6His) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Human GAS6 (C-6His)?

Recombinant Human GAS6 (C-6His) is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Human GAS6 (C-6His)?

Estimated delivery time for Recombinant Human GAS6 (C-6His) is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Human GAS6 (C-6His)?

The safety data sheet for Recombinant Human GAS6 (C-6His) is available here: https://789.bio/eb/j1Oyf1.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

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