Recombinant Human Butyrophilin Subfamily 1 Member A1/BTN1A1 (C-Fc)

Specifications

Catalog number

PKSH033945-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Butyrophilin Subfamily 1 Member A1 (BTN1A1) is the major protein associated with fat droplets in the milk. It belongs the immunoglobulin superfamily. BTN1A1 acts as a specific membrane-associated receptor for the association of cytoplasmic droplets with the apical plasma membrane. It is localized to the major histocompatibility complex (MHC) class I region of 6p. It may have arisen relatively recently in evolution by the shuffling of exons between 2 ancestral gene families. It is shown that BTN1A1 inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion.

Abbreviation

BTN1A1

Synonyms

BT; BTN; BTN1A1; Butyrophilin Subfamily 1 Member A1

UniProt

Q13410

Accession Number

Q13410

Expression System

HEK293 Cells

Tag

C-Fc

Sequence

Ala27-Arg242

Field of Research

Cardiovascular

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

50.8 kDa

Observed Molecular Weight

60-80 kDa

Species

Human