Recombinant Human Immunoglobulin Superfamily Member 8/IGSF8/CD316 (C-Fc)

Specifications

Catalog number

PKSH033946-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Immunoglobulin Superfamily Member 8 (IGSF8) is a single-pass membrane protein. IGSF8 contains four Ig-like C2 type domains. The Ig-like C2-type domains 3 and 4 are required for interactions with CD81. IGSF8 may regulate proliferation and differentiation of keratinocytes. IGSF8 may participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain. It also may play a role on integrin-dependent morphology and motility functions.

Abbreviation

Immunoglobulin

Synonyms

IGSF; CD81 Partner; Immunoglobulin Superfamily Member; Glu-Trp-Ile EWI Motif-Containing Protein; Keratinocytes-Associated Transmembrane Protein; CD81P; LIR-D; EWI; KCT; IGSF8; CD316; CD81P3; EWI-2; EWI2; KCT-4; LIR-D1; PGRL; CD81 Partner 3; Glu-Trp-Ile EWI Motif-Containing Protein 2; Immunoglobulin Superfamily Member 8; Keratinocytes-Associated Transmembrane Protein 4; Prostaglandin Regulatory-Like Protein; KCT4; PGRL

UniProt

Q969P0

Accession Number

Q969P0

Expression System

HEK293 Cells

Tag

C-Fc

Sequence

Arg28-Thr579

Field of Research

Microbiology; Cancer; immunology

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

85.7 kDa

Observed Molecular Weight

90-120 kDa

Species

Human