Recombinant Human CD3D&CD3E Heterodimer (C-Fc-Flag&C-Fc-6His)

Specifications

Catalog number

PKSH033951-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

T-cell surface glycoprotein CD3D & CD3E, also known as CD3 delta & CD3 epsilon chain, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon (CD3E), CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.

Abbreviation

CD3D&CD3E Heterodimer

Synonyms

CD3 delta & CD3 epsilon; CD3 delta / epsilon; CD3E & CD3D

UniProt

P04234; P07766

Accession Number

P04234&P07766

Expression System

HEK293 Cells

Tag

C-Fc-Flag & C-Fc-His

Sequence

Phe22-Ala105&Asp23-Asp126

Field of Research

Immunology; Stem cells

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

37&39.2 kDa

Observed Molecular Weight

40-60 kDa

Species

Human