Recombinant Human Leukocyte Ig-Like Receptor B1/ LILRB1/ILT2/CD85j (C-Fc)

Specifications

Catalog number

PKSH033978-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

The immunoglobulin-like transcript (ILT) family (also named leukocyte Ig-like receptors (LIR) and monocyte/macrophage Ig-like receptors (MIR) ) can be activating and inhibitory immunoreceptors. ILTs are expressed on many leukocyte subsets and regulators of immune responses . ILTs share significant homology with killer cell Ig-like receptors (KIR) . Except ILT-6, all ILT family members are type I transmembrane proteins having two or four extracellular Ig-like domains . ILT2 is expressed on most monocytes, dendritic cells, and mature B cells. ILT2 is also expressed on small percentages of T-cells and NK cells. ILT2 can prevents cellular activation.

Abbreviation

LILRB1; ILT2; CD85j

Synonyms

CD85 Antigen-Like Family Member J; CD85j; ILT-2; ILT2; Immunoglobulin-Like Transcript 2; LILRB1; LIR-1; Leukocyte Immunoglobulin-Like Receptor 1; Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 1; MIR-7; Monocyte/Macrophage Immunoglobulin-Like Receptor 7

UniProt

D9IDM8

Accession Number

D9IDM8

Expression System

HEK293 Cells

Tag

C-Fc

Sequence

Gly24-His458

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

74.1 kDa

Observed Molecular Weight

100-120 kDa

Species

Human