Recombinant Human Tie-2 (C-6His) — image 1 of 3

Product details

Recombinant Human Tie-2 (C-6His)

Q: What is the catalog number for Recombinant Human Tie-2 (C-6His)?

The catalog number for Recombinant Human Tie-2 (C-6His) is PKSH033993.

Q: What sizes are available for Recombinant Human Tie-2 (C-6His)?

Recombinant Human Tie-2 (C-6His) is available in the following size(s): 10 µg, 50 µg.

Q: How many pack sizes does Recombinant Human Tie-2 (C-6His) come in?

Recombinant Human Tie-2 (C-6His) is available in 2 different pack sizes.

Q: Is Recombinant Human Tie-2 (C-6His) in stock?

Recombinant Human Tie-2 (C-6His) is currently made to order / not held in immediate stock. Contact us for lead time.

Q: Who manufactures Recombinant Human Tie-2 (C-6His)?

Recombinant Human Tie-2 (C-6His) is manufactured by Elabscience.

Q: What is the estimated delivery time for Recombinant Human Tie-2 (C-6His)?

Estimated delivery time for Recombinant Human Tie-2 (C-6His) is approximately 15 business day(s), depending on your location.

Q: Where can I find the safety data sheet (SDS/MSDS) for Recombinant Human Tie-2 (C-6His)?

The safety data sheet for Recombinant Human Tie-2 (C-6His) is available here: https://789.bio/eb/Cu188K.

Q: What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Q: Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

Q: What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

Catalog number PKSH033993-01

Choose a variant (2 options)

Selecting a variant updates its price, size and availability.

Price for PKSH033993-01

Size / count 10 µg

Specifications

Catalog number: PKSH033993-01
Size / count: 10 µg
Dry ice: No
Hazardous: No
Discontinued: No
Background: Tie-1/Tie (tyrosine kinase with Ig and EGF homology domains 1) and Tie-2/Tek comprise a receptor tyrosine kinase (RTK) subfamily with unique structural characteristics: two immunoglobulin-like domains flanking three epidermal growth factor (EGF) -like domains and followed by three fibronectin type III-like repeats in the extracellular region and a split tyrosine kinase domain in the cytoplasmic region. These receptors are expressed primarily on endothelial and hematopoietic progenitor cells and play critical roles in angiogenesis, vasculogenesis and hematopoiesis. Human Tie-2 cDNA encodes a 1124 amino acid (aa) residue precursor protein with an 18 residue putative signal peptide, a 727 residue extracellular domain and a 354 residue cytoplasmic domain. Two ligands, angiopoietin-1 (Ang-1) and angiopoietin-2 (Ang-2), which bind Tie-2 with high-affinity have been identified. Ang-2 has been reported to act as an antagonist for Ang-1. Mice engineered to overexpress Ang-2 or to lack Ang-1 or Tie-2 display similar angiogenesis defects.
Abbreviation: Tie-2
Synonyms: CD202b; CD202b antigen; EC 2.7.10; EC 2.7.10.1; TEK; TEK tyrosine kinase; Tie-2; Tie2; VMCM; VMCM1; angiopoietin-1 receptor; endothelial; hTIE2; p140 TEK; soluble TIE2 variant 1; soluble TIE2 variant 2
Accession Number: NP_000450.2
Expression System: HEK293 Cells
Tag: C-His
Sequence: Ala23-Lys745
Field of Research: Signal Transduction; Cardiovascular; Cancer; Developmental Biology; Stem cells
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Purity: > 95 % as determined by reducing SDS-PAGE.
Bioactivity: Not validated for activity
Reconstitution: Please refer to the printed manual for detailed information.
Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight: 81.4 kDa
Observed Molecular Weight: 100-120 kDa
Species: Human

Frequently Asked Questions

What is the catalog number for Recombinant Human Tie-2 (C-6His)?

The catalog number for Recombinant Human Tie-2 (C-6His) is PKSH033993.

What sizes are available for Recombinant Human Tie-2 (C-6His)?

Recombinant Human Tie-2 (C-6His) is available in the following size(s): 10 µg, 50 µg.

How many pack sizes does Recombinant Human Tie-2 (C-6His) come in?

Recombinant Human Tie-2 (C-6His) is available in 2 different pack sizes.

Is Recombinant Human Tie-2 (C-6His) in stock?

Recombinant Human Tie-2 (C-6His) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Human Tie-2 (C-6His)?

Recombinant Human Tie-2 (C-6His) is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Human Tie-2 (C-6His)?

Estimated delivery time for Recombinant Human Tie-2 (C-6His) is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Human Tie-2 (C-6His)?

The safety data sheet for Recombinant Human Tie-2 (C-6His) is available here: https://789.bio/eb/Cu188K.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.