Recombinant Human Leukocyte Ig-Like Receptor A3/LILRA3/ILT6/CD85e (C-Fc)

Specifications

Catalog number

PKSH034013-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Leukocyte immunoglobulin-like receptor subfamily A member 3 is also known as CD85 antigen-like family member E, Immunoglobulin-like transcript 6, ILT-6, Leukocyte immunoglobulin-like receptor 4, LIR-4 and Monocyte inhibitory receptor HM43/HM31. In humans, it is encoded by the LILRA3 gene. It acts as soluble receptor for class I MHC antigens. Binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1 or LILRB2.It is detected in B-cells, natural killer (NK) cells, peripheral blood monocytes and lung.

Abbreviation

LILRA3; ILT6; CD85e

Synonyms

CD85 antigen-like family member E; ILT-6; Immunoglobulin-like transcript 6; LIR-4 and Monocyte inhibitory receptor HM43/HM31; Leukocyte immunoglobulin-like receptor 4; Leukocyte immunoglobulin-like receptor subfamily A member 3

UniProt

Q8N6C8

Accession Number

AAH28208.1

Expression System

HEK293 Cells

Tag

C-Fc

Sequence

Gly24-Glu439

Field of Research

Immunology

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

72.2 kDa

Observed Molecular Weight

84-98 kDa

Species

Human