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Product details

Recombinant Human IL-6RA (C-Fc)

Catalog number PKSH034017-01

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Price for PKSH034017-01

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Size / count 10 µg

Specifications

Catalog number
PKSH034017-01
Size / count
10 µg
Dry ice
No
Hazardous
No
Discontinued
No
Background
Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. IL6Ra is a part of the receptor for interleukin 6 cytokine. IL6Ra binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitates an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis. Low concentration of a soluble form of IL6 receptor acts as an agonist of IL6 activity. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer.
Abbreviation
IL-6RA
Synonyms
Membrane glycoprotein; CD126; gp80; IL6Q; IL-6R; IL-6R 1; IL-6R subunit alpha; IL-6R-1; IL6RA; IL-6RA; IL-6R-Alpha; IL6RQ; Interleukin-6 receptor subunit alpha; Membrane glycoprotein 80; IL6R; IL-6Rα alpha; CD 126; CD126 antigen; IL 6R; IL 6R 1; IL 6R alpha; IL-6 receptor alpha chain; IL-6 receptor subunit alpha; IL-6R 1 Membrane glycoprotein 80 (gp80) ; Interleukin 6 receptor; MGC30256
UniProt
P08887
Accession Number
P08887
Expression System
HEK293 Cells
Tag
C-Fc
Sequence
Leu20-Pro365
Field of Research
Immunology; Stem cells
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
65.4 kDa
Observed Molecular Weight
85-100 kDa
Species
Human

Frequently Asked Questions

What is the catalog number for Recombinant Human IL-6RA (C-Fc)?

The catalog number for Recombinant Human IL-6RA (C-Fc) is PKSH034017.

What sizes are available for Recombinant Human IL-6RA (C-Fc)?

Recombinant Human IL-6RA (C-Fc) is available in the following size(s): 10 µg, 50 µg.

How many pack sizes does Recombinant Human IL-6RA (C-Fc) come in?

Recombinant Human IL-6RA (C-Fc) is available in 2 different pack sizes.

Is Recombinant Human IL-6RA (C-Fc) in stock?

Recombinant Human IL-6RA (C-Fc) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Human IL-6RA (C-Fc)?

Recombinant Human IL-6RA (C-Fc) is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Human IL-6RA (C-Fc)?

Estimated delivery time for Recombinant Human IL-6RA (C-Fc) is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Human IL-6RA (C-Fc)?

The safety data sheet for Recombinant Human IL-6RA (C-Fc) is available here: https://789.bio/eb/q9yn90.

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

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