Recombinant Human LEPR (C-Fc) — image 1 of 3

Product details

Recombinant Human LEPR (C-Fc)

Q: What is the catalog number for Recombinant Human LEPR (C-Fc)?

The catalog number for Recombinant Human LEPR (C-Fc) is PKSH034018.

Q: What sizes are available for Recombinant Human LEPR (C-Fc)?

Recombinant Human LEPR (C-Fc) is available in the following size(s): 10 µg, 50 µg.

Q: How many pack sizes does Recombinant Human LEPR (C-Fc) come in?

Recombinant Human LEPR (C-Fc) is available in 2 different pack sizes.

Q: Is Recombinant Human LEPR (C-Fc) in stock?

Recombinant Human LEPR (C-Fc) is currently made to order / not held in immediate stock. Contact us for lead time.

Q: Who manufactures Recombinant Human LEPR (C-Fc)?

Recombinant Human LEPR (C-Fc) is manufactured by Elabscience.

Q: What is the estimated delivery time for Recombinant Human LEPR (C-Fc)?

Estimated delivery time for Recombinant Human LEPR (C-Fc) is approximately 15 business day(s), depending on your location.

Q: Where can I find the safety data sheet (SDS/MSDS) for Recombinant Human LEPR (C-Fc)?

The safety data sheet for Recombinant Human LEPR (C-Fc) is available here: https://789.bio/eb/b5uvLK.

Q: Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Q: Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

Q: What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

Catalog number PKSH034018-01

Choose a variant (2 options)

Selecting a variant updates its price, size and availability.

Price for PKSH034018-01

Size / count 10 µg

Specifications

Catalog number: PKSH034018-01
Size / count: 10 µg
Dry ice: No
Hazardous: No
Discontinued: No
Background: The Leptin receptor is a member of the Class I cytokine receptor family. It mediates the activities of Leptin, a multi-functional hormone produced primarily by adipose tissues that plays roles in food intake, energy metabolism, angiogenesis, reproduction, hematopoiesis, bone metabolism, and immune function. The human Leptin R gene encodes 1165 amino acids (aa) including a signal peptide, an extracellular region with cytokine receptor homology (CRH), multiple fibronectin type III domains and a WSXWS motif, a transmembrane domain, and a cytoplasmic domain that supports JAK/STAT signaling. Soluble Leptin R is the primary Leptin-binding protein in blood, where it maintains a pool of available bioactive Leptin, delays Leptin clearance from circulation, and down-regulates blood-brain transmission of Leptin. In humans, soluble Leptin R levels are inversely proportional to adiposity and are elevated in females versus males. Soluble Leptin R is also found up-regulated in patients with chronic heart failure, end-stage renal disease, and anorexia.It is expressed by tumor-initiating stem cells, and is proposed as a link between cancer and obesity.
Abbreviation: LEPR
Synonyms: CD295; DB; HuB219; LEP-R; LEPR; Leptin receptor; OB receptor; OB-R; OBR
UniProt: P48357
Accession Number: P48357
Expression System: HEK293 Cells
Tag: C-Fc
Sequence: Phe22-Asp839
Field of Research: Signal Transduction; Cardiovascular; Cancer; metabolism
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Purity: > 90 % as determined by reducing SDS-PAGE.
Bioactivity: Not validated for activity
Reconstitution: Please refer to the printed manual for detailed information.
Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight: 120.4 kDa
Observed Molecular Weight: 150-180 kDa
Species: Human

Frequently Asked Questions

What is the catalog number for Recombinant Human LEPR (C-Fc)?

The catalog number for Recombinant Human LEPR (C-Fc) is PKSH034018.

What sizes are available for Recombinant Human LEPR (C-Fc)?

Recombinant Human LEPR (C-Fc) is available in the following size(s): 10 µg, 50 µg.

How many pack sizes does Recombinant Human LEPR (C-Fc) come in?

Recombinant Human LEPR (C-Fc) is available in 2 different pack sizes.

Is Recombinant Human LEPR (C-Fc) in stock?

Recombinant Human LEPR (C-Fc) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Human LEPR (C-Fc)?

Recombinant Human LEPR (C-Fc) is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Human LEPR (C-Fc)?

Estimated delivery time for Recombinant Human LEPR (C-Fc) is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Human LEPR (C-Fc)?

The safety data sheet for Recombinant Human LEPR (C-Fc) is available here: https://789.bio/eb/b5uvLK.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.