Recombinant Human Intelectin-1/ITLN1 Protein (His Tag)

Specifications

Catalog number

PKSH034073-01

Size / count

50 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Intelectin-1 (ITLN1) is a secreted protein and contains 1 fibrinogen C-terminal domain. Intelectin-1 is a 40 kDa Ca- dependent galactofuranose-binding lectin that is not a C-type lectin. It is expressed on multiple cell types and appears to participate in insulin signaling and microbe recognition. The protein has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. It increases AKT phosphorylation in the absence and presence of insulin and it may play a role in the defense systemagainst microorganisms. It also may specifically recognize carbohydrate chains of pathogens and bacterial components containing galactofuranosy l residues, in a calcium-dependent manner.

Abbreviation

Intelectin-1; ITLN1

Synonyms

Endothelial lectin HL-1; Galactofuranose-binding lectin; ITLN-1; Intelectin-1; Intestinal lactoferrin receptor; Omentin.

UniProt

Q8WWA0

Accession Number

Q8WWA0

Expression System

E.coli

Tag

N-His

Sequence

Cys31-Gly253

Endotoxin

Please contact us for more information.

Purity

> 90 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

26.4 kDa

Species

Human