Recombinant Human IL-26 protein (His Tag)

Specifications

Catalog number

PKSH034111-01

Size / count

20 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

May play a role in local mechanisms of mucosal immunity and seems to have a pro-inflammatory function. May play a role in inflammatory bowel disease. Activates STAT1 and STAT3, MAPK1/3 (ERK1/2), JUN and AKT. Induces expression of SOCS3, TNF-alpha and IL-8, secretion of IL-8 and IL-10 and surface expression of ICAM1. Decreases proliferation of intestinal epithelial cells. Is inhibited by heparin.

Abbreviation

IL-26

Synonyms

Protein AK; AK155; IL-26; IL26; IL 26; Interleukin 26; Interleukin-26; Protein AK155

UniProt

Q9NPH9

Accession Number

Q9NPH9

Expression System

E.coli

Tag

C-His

Sequence

Lys 22-Gln 171

Applications

Cell culture

Field of Research

Immunology

Endotoxin

< 0.1 EU per μg of the protein as determined by the LAL method.

Purity

> 98 % as determined by reducing SDS-PAGE.

Bioactivity

50

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

18.5 kDa

Observed Molecular Weight

18 kDa

Species

Human