Recombinant Human VEGF165 protein (His Tag)

Specifications

Catalog number

PKSH034126-01

Size / count

20 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Vascular endothelial growth factor (VEGF) ; also known as vascular permeability factor (VPF) and VEGF-A; is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-derived growth factor (PDGF) /vascular endothelial growth factor (VEGF) family and often exists as a disulfide-linked homodimer. VEGF-A protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects; including mediating increased vascular permeability; inducing angiogenesis; vasculogenesis and endothelial cell growth; promoting cell migration; inhibiting apoptosis and tumor growth. VEGF-A protein is also a vasodilator that increases microvascular permeability; thus it was originally referred to as vascular permeability factor.

Abbreviation

VEGF165

Synonyms

Folliculostellate cell-derived growth factor; Glioma-derived endothelial cell mitogen; VPF

UniProt

P15692-4

Accession Number

NP_001165097

Expression System

E.coli

Tag

C-His

Sequence

Ala 27-Arg 191

Applications

Cell culture

Endotoxin

< 0.1 EU per μg of the protein as determined by the LAL method.

Purity

> 98 % as determined by reducing SDS-PAGE.

Bioactivity

6

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

20.1 kDa

Observed Molecular Weight

21 kDa

Species

Human