Recombinant Human FGF-12 protein (His Tag)

Specifications

Catalog number

PKSH034155-01

Size / count

20 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Fibroblast Growth Factor 12 (FGF-12) is a member of the fibroblast growth factor (FGF) family. FGF-12 is probably involved in nervous system development and function. FGF-12 lacks the N-terminal signal sequence present in most of the FGF family members, but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal. When transfectedinto mammalian cells, this protein accumulated in the nucleus, but was not secreted. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.

Abbreviation

FGF-12

Synonyms

EIEE47B; FHF1

UniProt

P61328

Accession Number

NP_004104.3

Expression System

E.coli

Tag

C-His

Sequence

Met 1-Thr 181

Applications

Cell culture

Field of Research

Cardiovascular, Signal Transduction

Endotoxin

< 0.1 EU per μg of the protein as determined by the LAL method.

Purity

> 98 % as determined by reducing SDS-PAGE.

Bioactivity

50

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

28.2 kDa

Observed Molecular Weight

21 kDa

Species

Human