Recombinant Human FGF-13 protein (His Tag)

Specifications

Catalog number

PKSH034156-01

Size / count

20 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules. Through its action on microtubules, may participate in the refinement of axons by negatively regulating axonal and leading processes branching. Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus. Regulates voltage-gated sodium channels transport and function. May also play a role in MAPK signaling. Required for the development of axonal initial segment-targeting inhibitory GABAergic synapses made by chandelier neurons.

Abbreviation

FGF-13

Synonyms

FHF-2; FHF2; LINC00889

UniProt

A8K1P5

Accession Number

NP_004105.1

Expression System

E.coli

Tag

C-His

Sequence

Met 1-Thr 245

Applications

Cell culture

Endotoxin

< 0.1 EU per μg of the protein as determined by the LAL method.

Purity

> 98 % as determined by reducing SDS-PAGE.

Bioactivity

50

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

28.4 kDa

Observed Molecular Weight

30 kDa

Species

Human