Recombinant Human/Mouse/Rat Activin A protein (His Tag)

Specifications

Catalog number

PKSH034165-01

Size / count

20 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. Activins, members of the TGF-beta superfamily, are disulfide-linked dimeric proteins originally purified from gonadal fluids as proteins that stimulated pituitary follicle stimulating hormone (FSH) release. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Activins are homodimers or heterodimers of the various beta subunit isoforms, while inhibins are heterodimers of a unique alpha subunit and one of the various beta subunits.

Abbreviation

Activin A

Synonyms

Activin A; INHBA; Inhibin beta A chain

UniProt

P08476

Accession Number

P08476

Expression System

E.coli

Tag

None

Sequence

Gly 311-Ser 426

Applications

Cell culture

Field of Research

Signal Transduction, Cancer

Endotoxin

< 0.1 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

501.0 x 103 IU/mg.3

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

13.1 kDa

Observed Molecular Weight

15 kDa

Species

Human/Mouse/Rat