Recombinant Mouse EphA3 Protein (aa 569-984, His & GST Tag)

Specifications

Catalog number

PKSM040288

Size / count

50 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

EPHA3 gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. EPHA3 gene encodes a protein that binds ephrin-A ligands. EPHA3 is involved in the retinotectal mapping of neurons. It may also control the segregation but not the guidance of motor and sensory axons during neuromuscular circuit development.

Synonyms

AW492086; Cek4; ETK1; End3; Hek; Hek4; Mek4; Tyro4

Accession Number

EDK98238.1

Expression System

Baculovirus-Insect Cells

Tag

N-His-GST

Sequence

Gly569-Val984

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 90 % as determined by reducing SDS-PAGE.

Bioactivity

Kinase activity untested

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

74.3 kDa

Observed Molecular Weight

66 kDa

Formulation

Supplied as sterile solution of 20mM Tris, 500mM NaCl, 10% glycerol, pH 8.0

Species

Mouse