Recombinant Mouse REG2/REG-2 Protein (Fc Tag)

Specifications

Catalog number

PKSM040340

Size / count

100 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

The REG2 Anticoagulation System consists of pegnivacogin, a subcutaneously administered aptamer factor IXa inhibitor, and its intravenous active control agent, anivamersen. The first-in-human study of the effect of the REG2 Anticoagulation System on thrombin generation demonstrates concentration-dependent suppression of thrombin generation that is reversible without rebound effect, as measured by the CAT assay. Full Name

Synonyms

REG2; RegII

UniProt

Q08731

Accession Number

NP_033069.1

Expression System

HEK293 Cells

Tag

C-hFc

Sequence

Met1-Ala173

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

43.6 kDa

Observed Molecular Weight

45.4 kDa

Species

Mouse