Recombinant Mouse LY-96/ESOP-1 Protein (Fc Tag)

Specifications

Catalog number

PKSM040358

Size / count

100 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

LY-96, also known as ESOP-1, is a protein which associates with toll-like receptor 4 on the cell surface and confers responsiveness to lipopolysaccyaride (LPS) . LY-96 also cooperates with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria. It enhances TLR4-dependent activation of NF-kappa-B. ESOP-1 has 160 amino acids, the sequence of which shows 64% identity with human ESOP-1/MD-2. ESOP-1 mRNA is highly expressed in the mouse embryos at 7.5 days after coitus.

Synonyms

ESOP-1; MD-2; MD2

UniProt

Q9JHF9

Accession Number

Q9JHF9

Expression System

HEK293 Cells

Tag

C-hFc

Sequence

Met1-Asn160

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

43.4 kDa

Observed Molecular Weight

47 kDa

Species

Mouse