Recombinant Mouse CREG/CREG1 Protein (Fc Tag)

Specifications

Catalog number

PKSM040377

Size / count

50 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

CREG1 belongs to the CREG family. It is a adenovirus E1A protein which both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. Thus it may contribute to the transcriptional control of cell growth and differentiation. The transcriptional control activity of cell growth requires interaction with IGF2R. CREG1 also antagonizes transcriptional activation and cellular transformation by E1A. It shares limited sequence similarity with E1A and binds both the general transcription factor TBP and the tumor suppressor pRb in vitro. CREG1 gene may contribute to the transcriptional control of cell growth and differentiation.

Synonyms

CREG1; cellular repressor of E1A-stimulated genes; cellular repressor of E1A-stimulated genes 1CREG; protein CREG1

UniProt

O88668

Accession Number

O88668

Expression System

HEK293 Cells

Tag

C-hFc

Sequence

Met1-Gln220

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 90 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

48.5 kDa

Observed Molecular Weight

59 kDa

Species

Mouse