Recombinant Mouse FCRL1 Protein (aa 1-204, His Tag)

Specifications

Catalog number

PKSM040425

Size / count

100 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Fc receptor-like protein 1, also known as FcR-like protein 1, Fc receptor homolog 1, IFGP family protein 1, Immune receptor translocation-associated protein 5 and FCRL1, is a single-pass type I membrane protein which contains threeIg-like C2-type (immunoglobulin-like) domains. It is a cell-surface membrane protein belonging to FCRL family and is preferentially expressed on B cells. FCRL1 is primarily expressed in secondary lymphoid tissues by mature subsets of B cells. It is detected in spleen, lymph node, heart, skeletal muscle, kidney, liver and placenta. FCRL1 is specifically expressed by mature B lineage cells with higher expression in naive versus memory B cells (at protein level) . Human Fc receptor-like molecules (FCRL1, FCRL2, FCRL3, FCRL4, FCRL5) have tyrosine-based immunoregulatory potential and are expressed by B-lineage subpopulations. FCRL1 may function as an activating coreceptor in B cells. It may also function in B cells activation and differentiation.

Synonyms

BXMAS1-like protein 1; Bxmas1; Bxmh1; Bxmh1b; CD307a; Fc receptor homolog 1; Fc receptor-like protein 1; FcR-like protein 1; FcRH1; FcRL1; Fcrh1; Fcrh1l; Fcrh1s; IFGP family protein 1; Ifgp1 Protein; mBXMH1; mIFGP1; moFcRH1

UniProt

Q8R4Y0

Accession Number

Q8R4Y0-2

Expression System

HEK293 Cells

Tag

C-His

Sequence

Met1-Thr204

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

21.6 kDa

Species

Mouse