Recombinant Mouse Carbonic Anhydrase VIII/CA8 Protein (His Tag)

Specifications

Catalog number

PKSM040495

Size / count

100 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

The carbonic anhydrases (or carbonate dehydratases) are classified as metalloenzyme for its zinc ion prosthetic group and form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons, a reversible reaction that takes part in maintaining acid-base balance in blood and other tissues. The carbonic anhydrasekl (CA) family consists of at least 11 enzymatically active members and a few inactive homologous proteins. Carbonic anhydrase protein (CA) VIII, which is a member of the CA gene family, has been shown to have no catalytic CA activity and its biological function is still unknown. Increased expression of CA-RP VIII was observed in 78% of colorectal carcinomas. It suggested that CA-RP VIII plays a role in the process of invasion in colorectal cancer.

Synonyms

AW546993; Ca8; Cals; Cals1; Car8; Carp; RP23-180H12.1; wdl

UniProt

P28651

Accession Number

P28651

Expression System

E.coli

Tag

C-His

Sequence

Met 1-Gln 291

Applications

Enzyme

Endotoxin

Please contact us for more information.

Purity

> 88 % as determined by reducing SDS-PAGE.

Bioactivity

Measured by its esterase activity. The specific activity is > 5 pmoles/min/μg.

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

34.5 kDa

Observed Molecular Weight

37 kDa

Species

Mouse