Recombinant Mouse Cathepsin B/CTSB Protein (His Tag)

Specifications

Catalog number

PKSM040956-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Cathepsin B (CatB) is an enzymatic protein belonging to the peptidase (or protease) families. It is the first described member of the family of lysosomal cysteine proteases. It is known to process a number of proteins, including pro and active caspases, prorenin and secretory leucoprotease inhibitor (SLPI) . It is believed to participate in intracellular degradation and turnover of proteins. Cathepsin B may play a role in activation and inactivation of caspases, activation of renin and inactivation of SLPI, the key steps in apoptosis, angiotensin production, and progression of emphysema, respectively. Cathepsin B may also have a role in invasion and metastasis.

Abbreviation

Cathepsin B; CTSB

Synonyms

Cathepsin B; Cathepsin B1; Ctsb

UniProt

P10605

Accession Number

P10605

Expression System

HEK293 Cells

Tag

C-His

Sequence

His18-Phe339

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

36.4 kDa

Observed Molecular Weight

32-50 kDa

Species

Mouse