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Product details

Recombinant Mouse Butyrophilin 1A1/BTN1A1 Protein (His Tag)

Catalog number PKSM040968-01

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Price for PKSM040968-01

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Size / count 10 µg

Specifications

Catalog number
PKSM040968-01
Size / count
10 µg
Dry ice
No
Hazardous
No
Discontinued
No
Background
Mouse Butyrophilin subfamily 1 member A1 (BTN1A1) is a type I transmembrane glycoprotein which is a member of the Ig superfamily. The BTN1A1 ECD displays two predicted IgV and IgC domains as do B7 and Skint proteins which interact with other Ig superfamily members. BTN1A1 binds to xanthine oxidoreductase (XOR) . This interaction stabilizes the association of XOR with the milk fat globule membrane and appears to be essential in the control of milk fat globule secretion. In vitro, BTN1A1 inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL-2 and IFN-γ secretion. Furthermore, in vivo, BTN1A1 has a protective effect against the development of experimental autoimmune encephalomyelitis (EAE) . Because butyrophilins are structurally related to B7 proteins and are functionally implicated in immune regulation, they may represent an emerging family of costimulatory/inhibitory molecules.
Abbreviation
Butyrophilin 1A1; BTN1A1
Synonyms
BTN; BTN1A1; Btn1a1; Butyrophilin subfamily 1 member A1; butyrophilin
UniProt
Q62556
Accession Number
Q62556
Expression System
HEK293 Cells
Tag
C-His
Sequence
Ala27-Trp247
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
25.4 kDa
Observed Molecular Weight
32-35 kDa
Species
Mouse

Frequently Asked Questions

What is the catalog number for Recombinant Mouse Butyrophilin 1A1/BTN1A1 Protein (His Tag)?

The catalog number for Recombinant Mouse Butyrophilin 1A1/BTN1A1 Protein (His Tag) is PKSM040968.

What sizes are available for Recombinant Mouse Butyrophilin 1A1/BTN1A1 Protein (His Tag)?

Recombinant Mouse Butyrophilin 1A1/BTN1A1 Protein (His Tag) is available in the following size(s): 10 µg, 50 µg.

How many pack sizes does Recombinant Mouse Butyrophilin 1A1/BTN1A1 Protein (His Tag) come in?

Recombinant Mouse Butyrophilin 1A1/BTN1A1 Protein (His Tag) is available in 2 different pack sizes.

Is Recombinant Mouse Butyrophilin 1A1/BTN1A1 Protein (His Tag) in stock?

Recombinant Mouse Butyrophilin 1A1/BTN1A1 Protein (His Tag) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Mouse Butyrophilin 1A1/BTN1A1 Protein (His Tag)?

Recombinant Mouse Butyrophilin 1A1/BTN1A1 Protein (His Tag) is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Mouse Butyrophilin 1A1/BTN1A1 Protein (His Tag)?

Estimated delivery time for Recombinant Mouse Butyrophilin 1A1/BTN1A1 Protein (His Tag) is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Mouse Butyrophilin 1A1/BTN1A1 Protein (His Tag)?

The safety data sheet for Recombinant Mouse Butyrophilin 1A1/BTN1A1 Protein (His Tag) is available here: https://789.bio/eb/KWvXf9.

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

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