Recombinant Mouse CCL24/Eotaxin-2 Protein

Specifications

Catalog number

PKSM040981-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Mouse CCL24 is a secreted protein, which is a member of the CC chemokine subfamily. Mouse Ccl24 cDNA encodes a 119 amino acid residue precursor protein, shares approximately 58% amino acid sequence identity with human Ccl24. It is predominantly expressed in the jejunum and spleen and also be induced in the lung by allergen challengeand IL4. Mouse ccl24 has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. Ccl24 is chemotactic for resting T-lymphocytes, eosinophils and can bind to CCR3. LPS and IL4 also differentially regulate the expression of Ccl24 in monocytes and macrophages.

Abbreviation

CCL24; Eotaxin-2

Synonyms

C-C motif chemokine 24; Ccl24; Eosinophil chemotactic protein 2; Eotaxin-2; Scya24; Small-inducible cytokine A24

UniProt

Q9JKC0

Accession Number

Q9JKC0

Expression System

E.coli

Tag

None

Sequence

Val27-Val119

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

10.3 kDa

Observed Molecular Weight

12 kDa

Species

Mouse